pentobarbital will lessen the level or influence of parecoxib by impacting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Observe.pentobarbital will minimize the level or effect of etonogestrel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.pentobarbital will reduce the level or effect of artemether/lumefantrine by